Fluorescence microscopical study of 5-hydroxytryptamine storage organelles in mepacrine-incubated blood platelets of beige mice (Chediak-Higashi syndrome)
- 1 May 1978
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 34 (5), 663-664
- https://doi.org/10.1007/bf01937020
Abstract
The number and fluorescence intensity of fluorescent granules (5-HT storage organelles) of mepacrine-incubated blood platelets of beige mice (Chediak-Higashi syndrome) are decreased compared to those of control mice platelets. This indicates both quantitative and qualitative changes of the 5-HT organelles, namely a reduced number and a reduced storage capacity, respectively.Keywords
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