The expression of human beta2 microglobulin on human spermatozoa

Abstract
The expression of human β2-microglobulin was detected on human spermatozoa from 7 donors using a cytotoxicity assay and indirect immunofluorescence. Inhibition experiments using purified β2-microglobulin demonstrated the specificities of these reactions. We were able to localize β2-microglobulin on human spermatozoa on the post-acrosomal region at a similar location to those described for HL-A antigen and for early embryonic antigen +t12, but also at the end of the intermediary piece and the beginning of the tail.