In vivo volume‐selective metabolite editing via correlated z‐order
- 1 December 1990
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 16 (3), 460-469
- https://doi.org/10.1002/mrm.1910160312
Abstract
Volume-selected 1H NMR spectroscopy was combined with spectral editing to selectively detect brain metabolites. The SPACE localization sequence was used to create a voxel of z-magnetization which could then be edited for any scalar coupled metabolite by the use of selective excitation in the ECZOTIC sequence to generate longitudinal spin order. The sequence returns an edited signal with no intrinsic loss of magnetization. The method was applied to observe approximately 10 m M ethanol and 17 mM lactate in the brain of a dog. © 1990 Academic Press, Inc.Funding Information
- Australian Research Council
- National Health and Medical Research Council
- Clive and Vera Ramaciotti Foundation
This publication has 19 references indexed in Scilit:
- Double‐quantum filtered volume‐selective NMR spectroscopyMagnetic Resonance in Medicine, 1989
- A Selective excitation/B0 gradient technique for high-resolution1H NMR studies of metabolites via zero-quantum coherence and polarization transferNMR in Biomedicine, 1989
- In vivo high‐resolution volume‐selected proton spectroscopy and T1 measurements in the dog brainMagnetic Resonance in Medicine, 1989
- A one‐shot lactate‐editing sequence for localized whole‐body spectroscopyMagnetic Resonance in Medicine, 1988
- Integrated volume‐selective/spectral editing 1H NMR and postdetection signal processing for the sensitive determination of lactateMagnetic Resonance in Medicine, 1988
- Quantitative estimation of lactate in the brain by 1H NMRMagnetic Resonance in Medicine, 1988
- A volume‐localized, two‐dimensional NMR method for the determination of lactate using zero‐quantum coherence created in a stimulated echo pulse sequenceMagnetic Resonance in Medicine, 1988
- Nodal inhomogeneity mapping by localized excitation—the “NIMBLE” shimming technique for high‐resolution in Vivo NMR spectroscopyMagnetic Resonance in Medicine, 1988
- Lipid and water suppression by selective 1H homonuclear polarization transferMagnetic Resonance in Medicine, 1987
- Product operator formalism for the description of NMR pulse experimentsProgress in Nuclear Magnetic Resonance Spectroscopy, 1984