ADDISONʼS DISEASE

Abstract
Fifty cases of Addison''s disease admitted to the Mount Sinai Hospital from 1924-1946 are analyzed with regard to age and sex distribution, subjective and objective symptoms and signs, laboratory findings, and treatment. The concomitant disturbances in carbohydrate metabolism related to absorption, storage, formation and utilization are stressed. The frequency of multi-glandular dysfunction and the role of concomitant endocrine disturbances in Addison''s disease are described. The part hypo-glycemia may play in acute Addisonian crisis is noted. The treatment of acute crisis, as well as chronic replacement therapy and the rationale for each is presented.