Synthesis of Optically Active α-Fluoro-α-methyl-β-hydroxyesters oferythroorthreoConfiguration with Baker's Yeast

Abstract

A number of optically pure α-fluoro-α-methyl-β-hydroxyesters of erythro or threo configuration were prepared by microbial transformation of α-fluoro-α-methyl-β-ketoesters with active fermenting baker's yeast.