Effects of Anoxia on Postarteriolar Pulmonary Vascular Resistance

Abstract

Studies on an isolated pulmonary lobe, perfused in situ from a carotid artery under regulated arterial pressure, showed that changes in its ventilation from room air to nitrogen promptly causes a slight but definite increase in pulmonary vascular resistance which, from the nature of the experimental arrangements, must lie beyond the pulmonary arterioles.