Evaluation of in vitro antifungal activity of LY121019
- 1 February 1988
- journal article
- research article
- Published by Springer Nature in European Journal of Clinical Microbiology & Infectious Diseases
- Vol. 7 (1), 77-80
- https://doi.org/10.1007/bf01962182
Abstract
LY121019 is a new semisynthetic lipoeptide antifungal agent with potent in vitro fungicidal activity against multiple clinical strains ofCandida albicans andCandida tropicalis but is 10–100 fold less active againstTorulopsis glabrata andCandida parapsilosis. Its in vitro activity againstCandida albicans andCandida tropicalis is comparable to that of amphotericin B. The in vitro fungicidal activity of this new agent supports further investigations into its use in treatment ofCandida infections.This publication has 3 references indexed in Scilit:
- In vitro and in vivo anti-Candida activity and toxicology of LY121019.The Journal of Antibiotics, 1984
- Antimicrobial Susceptibility Testing of Yeasts: a Turbidimetric Technique Independent of Inoculum SizeAntimicrobial Agents and Chemotherapy, 1976
- THE RATE OF BACTERICIDAL ACTION OF PENICILLIN IN VITRO AS A FUNCTION OF ITS CONCENTRATION, AND ITS PARADOXICALLY REDUCED ACTIVITY AT HIGH CONCENTRATIONS AGAINST CERTAIN ORGANISMSThe Journal of Experimental Medicine, 1948