Serotonergic and noradrenergic sensitivity in obsessive-compulsive disorder: behavioral findings
- 1 August 1988
- journal article
- research article
- Published by American Psychiatric Association Publishing in American Journal of Psychiatry
- Vol. 145 (8), 1015-1017
- https://doi.org/10.1176/ajp.145.8.1015
Abstract
Six of eight patients with obsessive-compulsive disorder had an exacerbation of symptoms when given-n-chlorophenylpiperazine. Fenfluramine and placebo produced mild improvement. Six patients given intravenous clonidine experienced marked reduction in obsessions. Implications for serotonergic and noradrenergic hypotheses of obsessive-compulsive disorder are discussed.This publication has 8 references indexed in Scilit:
- Serotonin Function in Obsessive-Compulsive DisorderArchives of General Psychiatry, 1988
- Serotonergic Responsivity in Obsessive-Compulsive DisorderArchives of General Psychiatry, 1988
- Serotonergic Responsivity in Obsessive-Compulsive DisorderArchives of General Psychiatry, 1987
- Clomipramine Treatment of Childhood Obsessive-Compulsive DisorderArchives of General Psychiatry, 1985
- Lactate infusions in obsessive-compulsive disorderAmerican Journal of Psychiatry, 1985
- Growth Hormone Response to Clonidine in Obsessive-Compulsive PatientsThe British Journal of Psychiatry, 1983
- Clonidine Ameliorates Gilles de la Tourette SyndromeArchives of General Psychiatry, 1980
- Clomipramine Treatment of Obsessive-Compulsive DisorderArchives of General Psychiatry, 1980