Isolation of a Cholinergic Proteolipid Receptor from Electric Tissue
- 1 March 1970
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 65 (3), 716-720
- https://doi.org/10.1073/pnas.65.3.716
Abstract
A proteolipid protein having a high affinity for methyl (14)C-hexamethonium, (3)H-p-(trimethylammonium)-benzene diazonium fluoroborate, and (acetyl-1-(14)C)choline chloride was isolated and purified from the electric tissue of Torpedo marmorata and Electrophorus electricus. At variance with the "receptor proteolipid" from the brain the one from electric tissue apparently does not bind atropine sulfate.Keywords
This publication has 10 references indexed in Scilit:
- Fractionation of lipids and proteolipids from cat grey and white matter by chromatography on an organophilic dextran gelJournal of Chromatography A, 1969
- Approaches to the molecular nature of pharmacological receptors.1969
- Isolation and chemical nature of the receptor for d‐tubocurarine in nerve‐ending membranes of the cerebral cortexJournal of Neurobiology, 1969
- Subcellular distribution and possible nature of the α-adrenergic receptor in the CNSLife Sciences, 1968
- Curare and Acetylcholine Receptor SubstanceNature, 1968
- Action of triton x-100 on lipids and proteolipids of nerve-ending membranesLife Sciences, 1968
- Affinity labeling of the acetylcholine-receptor.Proceedings of the National Academy of Sciences, 1967
- FINE STRUCTURAL LOCALIZATION OF ACETYLCHOLINESTERASE IN ELECTROPLAQUE OF THE ELECTRIC EELThe Journal of cell biology, 1966
- Affinity Labeling—a General Method for Labeling the Active Sites of Antibody and Enzyme Molecules*Biochemistry, 1962