Sensitivity of Neisseria gonorrhoeae to antibiotics in London (1976-78).

Abstract

Three surveys of the sensitivity of pre-treatment isolates of gonococci to penicillin, ampicillin, tetracycline, spectinomycin, streptomycin and co-trimoxazole were carried out during 1976-1978. Compared with results of previous surveys in the London area, the decline in proportion of gonococci strains insensitive to penicillin apparently halted. No changes were found in the levels of resistance to ampicillin, tetracycline or spectinomycin during the period surveyed, although there was slight increase in proportion of strains requiring concentrations of 20 .mu.g spectinomycin/ml for inhibition. Streptomycin resistance decreased considerably and 91% of strains are now sensitive to 10 .mu.g streptomycin/ml.