Abstract
Nervous and chemical (histamine, alcohol) stimulations of normally innervated gastric glands in a dog activate a flow of gastric juice, in which the acidity is slightly lowered at the end of the secretory period. In a dog with a Heidenhain pouch ingestion of different foods produces a flow of acid juice and finally a scanty secretion of slightly acid fluid rich in mucin. The variations in the acidity of the gastric juice, which are not very pronounced under normal conditions, are attributed to several factors discussed in this paper.