DisseminatedScedosporium inflatum infection in a patient with acute myeloblastic leukemia

Abstract
A case of disseminatedScedosporium inflatum infection occurring in a neutropenic patient with acute myeloblastic leukemia is reported.Scedosporium inflatum was isolated from skin lesions, blood, urine and vitreous cultures. Amphotericin B treatment was ineffective in avoiding hematogenous spread. At autopsy, hyphae and ovoid conidia with truncate bases consistent with the morphology ofScedosporium inflatum were found in the lungs, kidneys, myocardium, liver, thyroid, spleen, lymph nodes, brain and the left eye. This is the first report of disseminatedScedosporium inflatum infection and the first time this organism has been isolated from a patient in Europe.