Comparative in vitro activity of the new difluoro-quinolone temafloxacin (A-62254) against bacterial isolates from cancer patients
- 1 October 1988
- journal article
- research article
- Published by Springer Nature in European Journal of Clinical Microbiology & Infectious Diseases
- Vol. 7 (5), 684-686
- https://doi.org/10.1007/bf01964255
Abstract
The in vitro activity of temafloxacin, a new difluoro quinolone agent, against 725 bacterial isolates representing 32 species was evaluated in comparison with that of ciprofloxacin. Temafloxacin inhibited the majority ofEnterobacteriaceae isolates at a concentration of≤0.5 µg/ml. It was also extremely active againstAcinetobacter spp. andAeromonas hydrophila. Its activity was 2–8fold less than that of ciprofloxacin against most gram-negative isolates. Methicillin-susceptible and methicillin-resistantStaphylococcus aureus, coagulase-negativeStaphylococcus spp.,Streptococcus spp.,Listeria monocytogenes, Bacillus spp. and group JK corynebacteria were inhibited at concentrations equal to that of ciprofloxacin.This publication has 10 references indexed in Scilit:
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