TDP-43 Depletion Induces Neuronal Cell Damage through Dysregulation of Rho Family GTPases
Open Access
- 1 August 2009
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 284 (33), 22059-22066
- https://doi.org/10.1074/jbc.m109.012195
Abstract
No abstract availableKeywords
This publication has 44 references indexed in Scilit:
- TDP-43 Overexpression Enhances Exon 7 Inclusion during the Survival of Motor Neuron Pre-mRNA SplicingPublished by Elsevier ,2008
- TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysisThe Lancet Neurology, 2008
- TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expressionProceedings of the National Academy of Sciences, 2008
- TDP‐43 A315T mutation in familial motor neuron diseaseAnnals of Neurology, 2008
- TDP-43 in Familial and Sporadic Frontotemporal Lobar Degeneration with Ubiquitin InclusionsThe American Journal of Pathology, 2007
- TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosisBiochemical and Biophysical Research Communications, 2006
- Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral SclerosisScience, 2006
- Human, Drosophila, and C.elegans TDP43: Nucleic Acid Binding Properties and Splicing Regulatory FunctionJournal of Molecular Biology, 2005
- Inhibition of Protein Geranylgeranylation and RhoA/RhoA Kinase Pathway Induces Apoptosis in Human Endothelial CellsJournal of Biological Chemistry, 2002
- An Essential Role for Rac/Cdc42 GTPases in Cerebellar Granule Neuron SurvivalJournal of Biological Chemistry, 2001