Strain C3H-A vy fB Mice: Ninety Percent Incidence of Mammary Tumors Transmitted by Either Parent
- 9 October 1970
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 170 (3954), 185-187
- https://doi.org/10.1126/science.170.3954.185
Abstract
Mammary tumorigenesis in C3H-AvyfB female mice is not due to milk-borne mammary tumor virus but to factors transmitted at conception. Prominent among these is the Avy gene which may increase the virulence or transmissibility of a variant of mammary tumor virus vertically transmitted by either parent, or may increase the tumorigenic response of the mammary tissue. These factors together with the influence of hormones of pregnancy resulted in the high incidence observed.Keywords
This publication has 1 reference indexed in Scilit:
- A NEW VIABLE YELLOW MUTATION IN THE HOUSE MOUSEJournal of Heredity, 1962