PRELIMINARY COMMUNICATION The Novel Bis(benzoxazole) Cytotoxic Natural Product UK-1 Is a Magnesium Ion-Dependent DNA Binding Agent and Inhibitor of Human Topoisomerase II
- 31 August 1999
- journal article
- Published by Elsevier in Bioorganic Chemistry
- Vol. 27 (4), 326-337
- https://doi.org/10.1006/bioo.1999.1138
Abstract
No abstract availableThis publication has 23 references indexed in Scilit:
- UK-1, a Novel Cytotoxic Metabolite from Streptomyces sp. 517-02. IV. Antifungal Action of Methyl UK-1.The Journal of Antibiotics, 1998
- The total synthesis of UK-1Tetrahedron Letters, 1997
- UK-1, a Novel Cytotoxic Metabolite from Strcptomyces sp. 517-02. III. Antibacterial Action of Demethyl UK-1.The Journal of Antibiotics, 1997
- Self-Assembly of a Quinobenzoxazine-Mg2+ Complex on DNA: A New Paradigm for the Structure of a Drug-DNA Complex and Implications for the Structure of the Quinolone Bacterial Gyrase-DNA ComplexJournal of Medicinal Chemistry, 1995
- Coordination chemistry of 2-(2'-hydroxyphenyl)-2-benzoxazole with gallium(III) and aluminum(III): two uncommon Group 13 metal environments stabilized by a biologically relevant binding groupInorganic Chemistry, 1993
- UK-1, a novel cytotoxic metabolite from Streptomyces sp. 517-02. II. Structural elucidation.The Journal of Antibiotics, 1993
- UK-1, a novel cytotoxic metabolite from Streptomyces sp. 517-02. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties.The Journal of Antibiotics, 1993
- Theoretical aspects of DNA-protein interactions: Co-operative and non-co-operative binding of large ligands to a one-dimensional homogeneous latticeJournal of Molecular Biology, 1974
- Isolation and structure of nocobactin NA, a lipid-soluble iron-binding compound from Nocardia asteroidesBiochemical Journal, 1974
- Theory of continuous variations plots and a new method for spectrophotometric determination of extraction and formation constantsAnalytical Chemistry, 1971