EFFECT OF OXYTOCIN, VASOPRESSIN, AND OTHER DISULFID HORMONES ON UPTAKE AND EXTRUSION OF WATER BY MITOCHONDRIA

Abstract
Oxytocin, vasopressin, and insulin stimulated the respiration-dependent uptake of water by rat liver and kidney mitochondria. This resembles the swelling action of simple disulfides such as oxidized glutathione. It was suggested that amino acid sequence and peptide chain conformation may enhance the swelling action of the disulfide group.