Actinomycin D: Specific Inhibitory Effects on the Explanted Chick Embryo
- 15 November 1963
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 142 (3594), 967-969
- https://doi.org/10.1126/science.142.3594.967
Abstract
Chick embryos containing 11 to 13 somites were cultured for 48 hours on media containing various amounts of the antibiotic actinomycin D. Morphological observations as well as quantitative determinations of protein nitrogen, DNA, and RNA indicate that the antibiotic specifically inhibits the growth and development of the embryonic axis posterior to the 12th somite.Keywords
This publication has 18 references indexed in Scilit:
- Breakdown of Rat-Liver Ergosomes in vivo after Actinomycin Inhibition of Messenger RNA SynthesisScience, 1963
- Effects of actinomycin D on macromolecule synthesis and early development in sea urchin eggsBiochemical and Biophysical Research Communications, 1963
- Growth of explanted chick embryos on a chemically defined medium and effects of specific amino acid deficienciesDevelopmental Biology, 1962
- ‘Messenger RNA’ in a Fission YeastNature, 1962
- Actinomycin D Inhibition of Deoxyribonucleic Acid-Dependent Synthesis of Ribonucleic AcidScience, 1962
- Teratogenic action of actinomycin D in the embryonic chick II. Early developmentJournal of Experimental Zoology, 1961
- Effect of Actinomycin D on Cellular Nucleic Acid Synthesis and Virus ProductionScience, 1961
- Teratogenic action of actinomycin D in the embryonic chickJournal of Experimental Zoology, 1961
- Genetic regulatory mechanisms in the synthesis of proteinsJournal of Molecular Biology, 1961
- Growth and glycine incorporation in chick embryo explantsDevelopmental Biology, 1959