BCG-INDUCED ALLERGY AND IMMUNITY IN GUINEA-PIGS DURING FIRST YEAR AFTER VACCINATION

Abstract

Revaccination with BCG depends on the outcome of periodically repeated tuberculin testing. Acquired resistance to tuberculosis and tuberculin skin sensitivity are concomitant results of BCG vaccination, and a waning resistance may be faithfully reflected in a waning tuberculin sensitivity. However, in man and in animals, the waning of tuberculin sensitivity may be prevented merely by a repetition of the tuberculin test, while data indicate that tuberculin testing has no such influence on the course of BCG-induced resistance to tuberculosis.