Lactic dehydrogenase activities of rat heart and skeletal muscle after exercise and training.
- 1 April 1967
- journal article
- research article
- Published by American Physiological Society in Journal of Applied Physiology
- Vol. 22 (4), 623-627
- https://doi.org/10.1152/jappl.1967.22.4.623
Abstract
Forty-eight male albino rats were used in an investigation of the immediate and chronic effects of exercise on the lactic dehydrogenase activity of heart and skeletal muscle. The animals were allocated into two equal groups; one group was trained for 5 weeks and the remaining rats served as untrained controls. The training program consisted of an initial 30-min. swim which was extended to 60 min.by increasing the swim time 5 min. each day. Water temperature in the exercise tank was maintained at 35 C. Half of the trained and untrained animals were sacrificed 24 hr. after the last training session. The remaining rats were exercised for 30 min. immediately prior to sacrifice. On an absolute weight basis, the trained animals had heavier adrenals than the untrained controls but lighter spleens and heart ventricles. Analysis of regressed organ weights adjusted for differences in final body weights revealed that the trained animals had heavier adrenals than the controls and that the rats which were exercised prior to sacrifice had lighter spleens. Training produced a significant increase in LDH activity of the heart ventricles whereas skeletal muscle activity decreased. Exercise did not produce any change in LDH activity of either heart or skeletal muscle.This publication has 8 references indexed in Scilit:
- Myocardial lactate oxidation in situ and the effect thereon of reduced coronary flowAmerican Journal of Physiology-Legacy Content, 1966
- Exercise, hypophysectomy, and spleen weight.Journal of Applied Physiology, 1966
- Effects of exercise on oxidative activities in rat liver mitochondriaAmerican Journal of Physiology-Legacy Content, 1966
- Chronic effect of exercise on liver cholesterol of normal and hypercholesteremic ratsAmerican Journal of Physiology-Legacy Content, 1963
- Lactic dehydrogenase activities of heart and skeletal muscle of exercised ratsAmerican Journal of Physiology-Legacy Content, 1961
- Biochemical adaptation as a response to exercise. 1. Effect of swimming on the levels of lactic dehydrogenase, malic dehydrogenase and phosphorylase in muscles of 8-, 11- and 15-week-old ratsBiochemical Journal, 1959
- Succinic Dehydrogenase Activity of the Heart and Skeletal Muscle of Exercised RatsAmerican Journal of Physiology-Legacy Content, 1956
- ALTERATIONS IN ORGAN AND BODY GROWTH OF RATS FOLLOWING DAILY EXHAUSTIVE EXERCISE, X-IRRADIATION, AND POST-IRRADIATION EXERCISE1954