Die parapapilläre Region in Normal- und Glaukomaugen - Teil 2: Korrelation der planimetrischen Befunde zu intrapapillären, perimetrischen und allgemeinen Daten

Abstract

The planimetric values of the parapapillary region in 312 unselected eyes with chronic primary open-angle glaucoma and 125 normal eyes of an age/and refraction-matched control group were correlated to the intrapapillary, perimetric, and general data of these eyes. High myopics (< -8.00 D) and "ocular hypertensives" were excluded. Zone "Alpha" and "Beta" incipient to advanced or subtotal to total parapapillary (chorio-pigmentepithelioretinal atrophy) were significantly correlated (p < 0.001) to: 1) area and width of the neuroretinal rim as a whole and in four different optic disk sectors; 2) cup area; 3) horizontal and vertical c/d ratios; 4) glaucoma stage; 5) age, and 6) refraction. Zone "Beta" was additionally correlated to the perimetric indices. Its correlation coefficients were generally higher than those of zone "Alpha." Sex and side showed no significant relationships. Divided into four different radial sectors, both zones "Alpha" and "Beta" were significantly larger (p < 0.001) the smaller the neuroretinal rim area (intrapapillary) in the same sector was. Additionally, zone "Beta" was significantly (p < 0.001) most often largest in the sector where the rim area was smallest. Thus, besides the temporal there was also a spatial correlation between the intrapapillary and parapapillary glaucomatous alterations. "Conus pigmentosus" and the peripapillary scleral rim showed no significant glaucoma-associated correlations and are thus without importance for quantified optic disk evaluation in glaucoma. Zones "Alpha" and "Beta", as regions of early to advanced of subtotal to total parapapillary, chorio-pigmentepithelioretinal atrophy, are not only chronologically but also spatially correlated to intrapapillary glaucomatous changes and are important in optic disk evaluation in glaucoma.