Clonal Variation in Phenotype and Life Span of Human Embryonic Fibroblasts (MRC-5) Transduced with the Catalytic Component of Telomerase (hTERT)
- 1 August 2001
- journal article
- Published by Elsevier in Experimental Cell Research
- Vol. 268 (1), 14-25
- https://doi.org/10.1006/excr.2001.5264
Abstract
No abstract availableKeywords
This publication has 42 references indexed in Scilit:
- Human Keratinocytes That Express hTERT and Also Bypass a p16INK4a-Enforced Mechanism That Limits Life Span Become Immortal yet Retain Normal Growth and Differentiation CharacteristicsMolecular and Cellular Biology, 2000
- A telomerase component is defective in the human disease dyskeratosis congenitaNature, 1999
- Human Endothelial Cell Life Extension by Telomerase ExpressionJournal of Biological Chemistry, 1999
- Disease states associated with telomerase deficiency appear earlier in mice with short telomeresThe EMBO Journal, 1999
- Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cellsNature, 1998
- Extension of Life-Span by Introduction of Telomerase into Normal Human CellsScience, 1998
- Evidence for a Critical Telomere Length in Senescent Human FibroblastsExperimental Cell Research, 1995
- Telomeres shorten during ageing of human fibroblastsNature, 1990
- Identification of a specific telomere terminal transferase activity in tetrahymena extractsCell, 1985
- The limited in vitro lifetime of human diploid cell strainsExperimental Cell Research, 1965