Metabolic Alkalosis in Infants with Cystic Fibrosis

Abstract
Since submission of the article, "Hypoelectrolytemia and metabolic alkalosis in infants with cystic fibrosis," and, during the first eight months of academic practice, I have diagnosed six cystic fibrosis infants under 1 year of age, four of whom had documented episodes of hypoelectrolytemia and severe metabolic alkalosis. The data are included in the Table. Cases 1 and 2 had recurrent episodes of metabolic alkalosis before the diagnosis of cystic fibrosis was made. Cases 2 and 4 are black infants, in whom the diagnosis of cystic fibrosis would not have been suspected, had not the association between cystic fibrosis and metabolic alkalosis of infancy been recognized.