The mechanism of the inhibition of dehydrogenases by salicylate
- 1 June 1967
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 19 (6), 355-366
- https://doi.org/10.1111/j.2042-7158.1967.tb09561.x
Abstract
Salicylate inhibits rabbit muscle lactate dehydrogenase, horse liver alcohol dehydrogenase, pig heart malate dehydrogenase and pig heart isocitrate dehydrogenase in vitro. The inhibitions are reversible, involving competition with nad, nadh2 or nadp. The results are discussed with reference to some of the in vivo actions of the drug.This publication has 21 references indexed in Scilit:
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