A Synthetic Peptide as Substrate for Tryptic Proteinase

Abstract

The post-stimulus persistence of vestibular nystagmus has been generally assumed to be due either (a) to a concomitant persistence of the receptor process or (b) to the action of an after-discharge mechanism located within the central nervous system. Investigation of the action-currents produced in the vestibular nerve (of the turtle) during various types of vestibular stimulation indicates that receptor activity probably never lasts for more than a fraction of a second after the cessation of the objective stimulus. This finding suggests that the relatively prolonged duration of nystagmus following certain kinds of vestibular stimulation is dependent upon the action of a central after-discharge mechanism.