Discorhabdins S, T, and U, New Cytotoxic Pyrroloiminoquinones from a Deep-Water Caribbean Sponge of the Genus Batzella

Abstract
Discorhabdins S, T, and U (1−3), three new discorhabdin analogues, have been isolated from a deep-water marine sponge of the genus Batzella. These discorhabdin analogues showed in vitro cytotoxicity against PANC-1, P-388, and A-549 cell lines. The isolation and structure elucidation of discorhabdins S, T, and U are described.