Diagnosis and Treatment of Primary Vaginal Carcinoma in Situ and Dysplasia

Abstract

Fifteen cases of primary carcinoma in situ or severe or moderate dysplasia of the vagina were diagnosed and treated during the period of 1966-1975 in Finland. Because of abnormal vaginal cytology, the lesion was localized by means of colposcopy and I staining. For 6 patients, local estrogen treatment was applied to increase the thickness of the epidermal layer. For 6 patients, treatment consisted of simple excision. Nine patients, including both those with carcinoma in situ, were treated with intravaginal radiation therapy. The radiation dosage was 2000-2600 rad at a distance of 1 cm from the surface of the epithelium. None of the patients showed any complications; all are now symptom-free.