Ciprofloxacin Concentrations in Human Aqueous Humor following Intravenous Administration
- 1 January 1987
- journal article
- research article
- Published by S. Karger AG in Chemotherapy
- Vol. 33 (5), 328-330
- https://doi.org/10.1159/000238517
Abstract
16 patients received an intravenous infusion of 200 mg ciprofloxacin 1, 2, 3 and 6 h, respectively, before cataract extraction. This dosage produced mean aqueous humor levels of 0.165 ± 0.09 and 0.12610.028 μg/ml after 1 and 3 h, respectively. The mean serum levels were 1.76010.873 and 0.85410.283 μg/mlafter 1 and 3 h, respectively. These levels are above the minimum inhibitory concentration of ciprofloxacin for sensitive organisms.Keywords
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