Brugia malayi: Relationship between Anti-Sheath Antibodies and Amicrofilaremia in Natives Living in an Endemic Area of South Kalimantan, Borneo *
- 1 July 1980
- journal article
- research article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 29 (4), 553-562
- https://doi.org/10.4269/ajtmh.1980.29.553
Abstract
A seroepidemiological approach was taken to elucidate the relationship between anti-microfilarial antibodies and amicrofilaremia in humans living under natural conditions of exposure to Brugia malayi. Entomological observations indicated that all of the people in the study population in South Kalimantan, Borneo, were exposed repeatedly to filarial infection. A third of the population had antibodies to the sheath of microfilariae. The prevalence and titer of anti-sheath IgM was higher than anti-sheath IgG or IgA. There was a statistically significant correlation between anti-sheath antibody and amicrofilaremia and these antibodies may play a role in regulating peripheral microfilaremia.This publication has 4 references indexed in Scilit:
- Immune reactions in human filariasisJournal of Clinical Microbiology, 1978
- Serological Diagnosis of Bancroftian and Malayan Filariasis *The American Journal of Tropical Medicine and Hygiene, 1978
- Dipetalonema viteae in hamsters: effect of antiserum or immunization with parasite extracts on production of microfilariaeParasitology, 1978
- STUDIES ON DIPETALONEMA-VITEAE-(FILARIOIDEA) .2. ANTIBODY DEPENDENT ADHESION OF PERITONEAL EXUDATE CELLS TO MICROFILARIAE INVITRO1978