Stepwise Oxidation of the Heteroatoms in O-Protected Pyridoxine-Like Pyridinophane Containing Thio Groups in the Intramolecular Bridge Chain
- 1 February 1987
- journal article
- research article
- Published by Oxford University Press (OUP) in Bulletin of the Chemical Society of Japan
- Vol. 60 (2), 818-820
- https://doi.org/10.1246/bcsj.60.818
Abstract
Racemic 14-Hydroxy-15-hydroxymethyl-O,O′-isopropylidene-2,8-dithia[9](2,5)pyridinophane, a model compound of our chiral pyridoxamine analogs, was oxidized under various conditions in order to examine the reactivities of the sulfur and the nitrogen atoms. Various degree of oxidized compounds, from monoxide to pentaoxide, including the desired S,S,S′,S′-tetraoxide, were obtained.Keywords
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