Radioimmunoassay of Fibrinogen and Its Proteolysis Products
- 1 January 1968
- journal article
- schattauer gmbh
- Published by Georg Thieme Verlag KG in Thrombosis and Haemostasis
- Vol. 20 (01/02), 001-006
- https://doi.org/10.1055/s-0038-1651243
Abstract
The solid-phase radioimmunoassay method has been applied to the measurement of fibrinogen. The method is extremely sensitive, being able to detect fibrinogen concentrations as low as 10 ng/ml. The immunoreactivity of fibrinogen proteolysis products differs from that of native fibrinogen, early proteolysis products showing enhanced immunoreactivity which decreases progressively with further digestion.Keywords
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