Inhibition of the Adherence of P-FimbriatedEscherichia colito Uroepithelial-Cell Surfaces by Proanthocyanidin Extracts from Cranberries

Abstract
The consumption of cranberry juice has been recommended for the prevention of urinary tract infections, and a 1994 clinical study1 provides scientific validation of this claim. The effect is due not to the highly acidic nature of cranberries but to specific compounds in cranberries that inhibit the adherence of Escherichia coli to uroepithelial cells.2,3