Improved Arene Fluorination Methodology for I(III) Salts
- 9 July 2010
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 12 (15), 3352-3355
- https://doi.org/10.1021/ol101154h
Abstract
The use of low polarity aromatic solvents (benzene or toluene) and/or the removal of inorganic salts results in dramatically improved yields of fluorinated arenes from diaryliodonium salts. This methodology is shown to “scale down” to the conditions used typically for radiotracer synthesis.Keywords
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