Effects of Exercise Training on Older Patients With Major Depression

Abstract

AGING OF THE population and the increased prevalence of chronic diseases among the elderly are major challenges facing our society and medical community. Depression is a significant cause—and consequence—of disability among older individuals. Estimates of the prevalence of mood disorders in the United States range from approximately 5% to 10% of elderly community dwellers^1,2 to 18% of nursing home residents.³ Depressive symptoms are associated with the presence of 1 or more chronic diseases^4,5 as well as disability,² including days in bed and days away from normal activities.⁵ Moreover, major depressive disorder (MDD) has been associated with a 59% increase in mortality risk during a 1-year follow-up.³