Fusion Image of Positron Emission Tomography and Computed Tomography for the Diagnosis of Local Recurrence of Rectal Cancer
- 9 May 2005
- journal article
- Published by Springer Science and Business Media LLC in Annals of Surgical Oncology
- Vol. 12 (7), 561-569
- https://doi.org/10.1245/aso.2005.08.001
Abstract
The aim of this study was to evaluate the clinical and therapeutic value of digital fusion image (FI) of positron emission tomography (PET) using (18)F-fluorodeoxy glucose and computed tomography (CT) in patients who were suspected of having a local recurrence of rectal cancer. Forty-two patients (32 men and 10 women; mean age, 61.4 years, range, 40-79 years) with a suspicion of local recurrence after curative resection of rectal cancer were prospectively recruited and underwent (18)F-fluorodeoxy glucose-PET and CT. The FI was reconstructed with a commercially available digital software program, T-B Fusion. Wilcoxon signed rank test was used to compare FI with CT alone or PET alone. FI yielded a correct diagnosis in 39 (93%) of 42 patients, whereas CT alone and PET alone did so in 33 (79%) and 37 (88%) patients, respectively. FI had better diagnostic accuracy than CT alone (P = .0138) and PET alone (P = .0156). Overall, FI altered patient management in 11 (26.2%) patients on the basis of additional information, including differentiation of the tumor from the postoperative scar in 6 patients, exact anatomical location in 3 patients, and both in 2 patients. FI has a potential clinical value in the treatment of suspected local recurrence of rectal cancer.Keywords
This publication has 27 references indexed in Scilit:
- Staging of Non–Small-Cell Lung Cancer with Integrated Positron-Emission Tomography and Computed TomographyNew England Journal of Medicine, 2003
- Local recurrence of rectal cancer:evaluation with F-18 fluorodeoxyglucose PET imagingAbdominal Radiology, 1997
- Curative reoperations for locally recurrent rectal cancerDiseases of the Colon & Rectum, 1996
- Pelvic Resection of Recurrent Rectal CancerAnnals of Surgery, 1994
- Recurrent rectal cancer and scar: differentiation with PET and MR imaging.Radiology, 1992
- Suspected recurrent rectosigmoid carcinoma after abdominoperineal resection: MR imaging and histopathologic findings.Radiology, 1989
- Recurrent rectal cancer: diagnosis with MR imaging versus CT.Radiology, 1988
- Recurrent colorectal carcinoma: evaluation with barium enema examination and CT.Radiology, 1987
- Colorectal carcinoma evaluation with CT: preoperative staging and detection of postoperative recurrence.Radiology, 1986
- Value of Computed Tomography in the Detection and Staging of Recurrent Rectal CarcinomasJournal of Computer Assisted Tomography, 1981