Simultaneous evaluation for terminal deoxynucleotidyl transferase and myeloperoxidase in leukemia
- 1 June 1982
- journal article
- research article
- Published by Wiley in American Journal of Hematology
- Vol. 12 (4), 391-396
- https://doi.org/10.1002/ajh.2830120410
Abstract
A technique for dual staining of cells using terminal deoxynucleotidyl transferase (TdT) and myeloperoxidase (MPO) is described. The technique has been applied to cells of two patients. One patient had chronic myelomonocytic leukemia evolving into acute myelomonocytic leukemia. The other patient had chronic myelogenous leukemia in blast crisis. Our findings indicate that TdT and MPO are exclusive markers except for a rare precursor cell with dual staining in one patient. This study supports the concept of acute mixed leukemia.Keywords
This publication has 7 references indexed in Scilit:
- Terminal deoxynucleotidyl transferase‐positive acute myeloblastic leukemiaAmerican Journal of Hematology, 1981
- Terminal Deoxynucleotidyl Transferase Immunofluorescence of Bone Marrow Smears: Experience in 156 CasesAmerican Journal of Clinical Pathology, 1979
- Terminal deoxynucleotidyl transferase as a hematopoietic cell markerBlood, 1979
- TERMINAL-DEOXYNUCLEOTIDYL-TRANSFERASE POSITIVE ACUTE LYMPHOBLASTIC LEUKÆMIA WITH AUER RODSThe Lancet, 1978
- Terminal deoxynucleotidyl transferase in the diagnosis of leukemia and malignant lymphomaAmerican Journal Of Medicine, 1978
- Terminal Transferase as a Predictor of Initial Responsiveness to Vincristine and Prednisone in Blastic Chronic Myelogenous LeukemiaNew England Journal of Medicine, 1978
- Acute lymphoblastic leukemia–hand mirror cell variant: A detailed cytological and ultrastructural study with an analysis of the immunologic surface markersAmerican Journal of Hematology, 1978