Structure-activity relationship of short-chain sphingoid bases as inhibitors of sphingosine kinase
- 1 November 1999
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 9 (21), 3175-3180
- https://doi.org/10.1016/s0960-894x(99)00554-5
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- Synthesis and apoptogenic activity of fluorinated ceramide and dihydroceramide analoguesBioorganic & Medicinal Chemistry Letters, 1999
- Effect of Aromatic Short-Chain Analogues of Ceramide on Axonal Growth in Hippocampal NeuronsJournal of Medicinal Chemistry, 1999
- Sphingosine 1-Phosphate-induced Cell Rounding and Neurite Retraction Are Mediated by the G Protein-coupled Receptor H218Journal of Biological Chemistry, 1999
- N,N-Dimethylsphingosine Is a Potent Competitive Inhibitor of Sphingosine Kinase but Not of Protein Kinase C: Modulation of Cellular Levels of Sphingosine 1-Phosphate and CeramideBiochemistry, 1998
- Dual Actions of Sphingosine-1-Phosphate: Extracellular through the Gi-coupled Receptor Edg-1 and Intracellular to Regulate Proliferation and SurvivalThe Journal of cell biology, 1998
- Involvement of Sphingosine 1-Phosphate in Nerve Growth Factor-Mediated Neuronal Survival and DifferentiationJournal of Neuroscience, 1997
- Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphateNature, 1996
- Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogensNature, 1993
- Synthesis of D‐Erythro‐ and D‐Threo‐Sphingosine Derivatives From L‐SerineHelvetica Chimica Acta, 1988
- The synthesis and configurational stability of differentially protected .beta.-hydroxy-.alpha.-amino aldehydesThe Journal of Organic Chemistry, 1987