Mutation in the DC-SIGN cytoplasmic triacidic cluster motif markedly attenuates receptor activity for phagocytosis and endocytosis of mannose-containing ligands by human myeloid cells
Open Access
- 4 September 2008
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Leukocyte Biology
- Vol. 84 (6), 1594-1603
- https://doi.org/10.1189/jlb.0308192
Abstract
Journal of Leukocyte Biology considers manuscripts of original investigations focusing on the origins, developmental biology, biochemistry and functions of granulocytes, lymphocytes, mononuclear phagocytes, and other cells involved in host defense. These include full-length papers on original research, rapid communications of new discoveries, letters, commentaries, and invited reviews.Keywords
Funding Information
- NIH/National Institute of Allergy and Infectious Diseases (AI-052458)
This publication has 30 references indexed in Scilit:
- The DC-SIGN–related lectin LSECtin mediates antigen capture and pathogen binding by human myeloid cellsBlood, 2007
- The C-type Lectin Receptors CLEC-2 and Dectin-1, but Not DC-SIGN, Signal via a Novel YXXL-dependent Signaling CascadeJournal of Biological Chemistry, 2007
- Infection of Dendritic Cells (DCs), Not DC-SIGN-Mediated Internalization of Human Immunodeficiency Virus, Is Required for Long-Term Transfer of Virus to T CellsJournal of Virology, 2006
- Modulation of Cellular Protein Trafficking by Human Immunodeficiency Virus Type 1 Nef: Role of the Acidic Residue in the ExxxLL MotifJournal of Virology, 2006
- Dectin-1 uses novel mechanisms for yeast phagocytosis in macrophagesBlood, 2004
- Dual function of C-type lectin-like receptors in the immune systemCurrent Opinion in Cell Biology, 2003
- Oligolysine-based Oligosaccharide ClustersJournal of Biological Chemistry, 2003
- C-type lectin receptors on dendritic cells and langerhans cellsNature Reviews Immunology, 2002
- A Di-aromatic Motif in the Cytosolic Tail of the Mannose Receptor Mediates Endosomal SortingJournal of Biological Chemistry, 2000
- Receptor-mediated pinocytosis of mannose glycoconjugates by macrophages: Characterization and evidence for receptor recyclingCell, 1980