A Transcriptional Pause Synchronizes Translation with Transcription in the Tryptophanase Operon Leader Region
Open Access
- 1 November 2003
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 185 (21), 6472-6476
- https://doi.org/10.1128/jb.185.21.6472-6476.2003
Abstract
Regulation of transcription of the tryptophanase operon requires that translation of its leader peptide coding region, tnaC , be coupled with its transcription. We show in vitro that a transcription pause site exists at the end of the tnaC coding region and that translation of tnaC releases the paused transcription complex, coupling transcription with translation.Keywords
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