Estimating Diarrhea Mortality among Young Children in Low and Middle Income Countries
Open Access
- 3 January 2012
- journal article
- research article
- Published by Public Library of Science (PLoS) in PLOS ONE
- Vol. 7 (1), e29151
- https://doi.org/10.1371/journal.pone.0029151
Abstract
Diarrhea remains one of the leading causes of morbidity and mortality among children under 5 years of age, but in many low and middle-income countries where vital registration data are lacking, updated estimates with regard to the proportion of deaths attributable to diarrhea are needed. We conducted a systematic literature review to identify studies reporting diarrhea proportionate mortality for children 1–59 mo of age published between 1980 and 2009. Using the published proportionate mortality estimates and country level covariates we constructed a logistic regression model to estimate country and regional level proportionate mortality and estimated uncertainty bounds using Monte-Carlo simulations. We identified more than 90 verbal autopsy studies from around the world to contribute data to a single-cause model. We estimated diarrhea proportionate mortality for 84 countries in 6 regions and found diarrhea to account for between 10.0% of deaths in the Americas to 31.3% of deaths in the South-east Asian region. Diarrhea remains a leading cause of death for children 1–59 mo of age. Published literature can be used to create a single-cause mortality disease model to estimate mortality for countries lacking vital registration data.Keywords
This publication has 10 references indexed in Scilit:
- Estimating the distribution of causes of death among children age 1-59 months in high-mortality countries with incomplete death certificationInternational Journal of Epidemiology, 2010
- Global, regional, and national causes of child mortality in 2008: a systematic analysisThe Lancet, 2010
- Causes of deaths in children younger than 5 years in China in 2008The Lancet, 2010
- Levels and trends in under-5 mortality, 1990–2008The Lancet, 2010
- Estimating child mortality due to diarrhoea in developing countriesBulletin of the World Health Organization, 2008
- The Limits and Intensity of Plasmodium falciparum Transmission: Implications for Malaria Control and Elimination WorldwidePLoS Medicine, 2008
- Estimating the causes of 4 million neonatal deaths in the year 2000International Journal of Epidemiology, 2006
- WHO estimates of the causes of death in childrenThe Lancet, 2005
- Falling diarrhoea mortality in Northeastern Brazil: did ORT play a role ?Health Policy and Planning, 1996
- Impact of oral rehydration and selected public health interventions on reduction of mortality from childhood diarrhoeal diseases in Mexico.1996