Host Resistance to Bacteria in Hemorrhagic Shock IV. Effect of Hypothermia on Clearance of Intravenously Injected Bacteria.

Abstract

Dogs precooled to 28[degree] C subjected to reversible severe hemorrhagic shock, (i.e. transfused after 2 hours), survive the intravenous injection of bacteria, whether the injection is made during shock or after recovery in response to the tranfusion. Normothermic dogs so treated do not recover. Precooling to 28[degree]C, therefore, protects the antibacterial mechanisms.