Immunological unresponsiveness to thymus-independent antigens: two fundamentally different genetic mechanisms of B-cell unresponsiveness to dextran
Open Access
- 1 December 1977
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 146 (6), 1663-1677
- https://doi.org/10.1084/jem.146.6.1663
Abstract
The immune response of mice to the α-l-6 epitope of dextran (Dx) B512 was found to be under genetic control. The congenic mouse strains A, A.CA, A.SW, A.TH, and A.TL exhibited a specific defect in their response to α-l-6. Also strain CBA/N was unresponsive to α-1-6, but the mechanism of unresponsiveness was found to be different.This publication has 13 references indexed in Scilit:
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