Interleukin-23 Restrains Regulatory T Cell Activity to Drive T Cell-Dependent Colitis
Top Cited Papers
Open Access
- 1 April 2008
- Vol. 28 (4), 559-570
- https://doi.org/10.1016/j.immuni.2008.02.019
Abstract
No abstract availableKeywords
This publication has 55 references indexed in Scilit:
- Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acidThe Journal of Experimental Medicine, 2007
- A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β– and retinoic acid–dependent mechanismThe Journal of Experimental Medicine, 2007
- IL‐27 controls the development of inducible regulatory T cells and Th17 cells via differential effects on STAT1European Journal of Immunology, 2007
- Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controlsNature, 2007
- Interleukin-23 drives innate and T cell–mediated intestinal inflammationThe Journal of Experimental Medicine, 2006
- IL-23 plays a key role inHelicobacter hepaticus–induced T cell–dependent colitisThe Journal of Experimental Medicine, 2006
- IL-23 is essential for T cell–mediated colitis and promotes inflammation via IL-17 and IL-6Journal of Clinical Investigation, 2006
- Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cellsNature, 2006
- Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brainNature, 2003
- Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory diseaseNature, 1992