Radioimmunoassay of morphine and morphine-like substances in biological fluids and human tissues
- 1 April 1977
- journal article
- research article
- Published by Springer Nature in La Ricerca in Clinica e in Laboratorio
- Vol. 7 (2), 179-190
- https://doi.org/10.1007/bf02879482
Abstract
Summary A radioimmunoassay is described for the determination of morphine and morphine-like substances in plasma, serum, biological fluids and tissue homogenates using an antiserum to morphine-6-hemisuccinyl-BSA and125I-morphine as the labelled tracer. In the B/F separation with ammonium sulphate, calcium sulphate was added to make the precipitate more compact. Some parameters related to the use of this method in direct assay on plasma, serum, other biological fluids and tissue homogenates were evaluated.Keywords
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- Urine Testing: A Comparison of Five Current Methods for Detecting MorphineAmerican Journal of Clinical Pathology, 1973
- A Measurement of the Specificities of Antibodies to Morphine-6-Succinyl-BSA by Competitive Inhibition of 14C-Morphine BindingThe Journal of Immunology, 1973
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