Chemical identity of the acrasin of the cellular slime mold Polysphondylium violaceum.
- 1 December 1982
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 79 (23), 7376-7379
- https://doi.org/10.1073/pnas.79.23.7376
Abstract
The aggregation chemoattractant (or acrasin) of P. violaceum, a species of cellular slime mold that does not respond chemotactically to cAMP, was identified. It was extracted and purified from aggregating amoebae, then analyzed for amino acid composition and by IR and mass spectrometry. The active molecule is N-propionyl-.gamma.-L-glutamyl-L-ornithine-.delta.-lactam ethyl ester (MW 327), which was named glorin. The compound was synthesized and shows normal chemotactic activity with the amoebae of P. violaceum.This publication has 20 references indexed in Scilit:
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