A Plasma Extract with Erythropoietic Activity
- 1 June 1954
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 86 (2), 255-258
- https://doi.org/10.3181/00379727-86-21066
Abstract
Admn. to intact rats of an extract, prepared from the plasma of phenylhydrazine-treated rabbits, results in significant increases in peripheral red cell counts, hemoglobin concns., reticulocyte percentages, hematocrit values, and in the concns. of nucleated erythrocytes within the marrow. The extract exerts no significant influence upon the total and differential white cell numbers of the sedimentation rates and red cell fragility values. The factor may be related to, or identical with, the circulating "hemopoietine", hypothesized to be the humoral mediator of anoxia, the fundamental erythrocytogenic stimulus.Keywords
This publication has 5 references indexed in Scilit:
- Humoral Regulation of Red Cell ProductionBlood, 1953
- Fundamental Stimulus for ErythropoiesisPhysiological Reviews, 1952
- INCORPORATION IN VITRO OF LABELED AMINO ACIDS INTO PROTEINS OF RABBIT RETICULOCYTESJournal of Biological Chemistry, 1952
- THE RELATION OF THE ADRENAL TO BLOOD FORMATION IN THE RAT1Endocrinology, 1951
- ON THE ALLEGED PRESENCE OF "HEMOPOIETINE" IN THE BLOOD SERUM OF RABBITS EITHER RENDERED ANEMIC OR SUBJECTED TO LOW PRESSURESAmerican Journal of Physiology-Legacy Content, 1934