Binding and ingestion of human lactoferrin by mouse alveolar macrophages.
- 1 April 1979
- Vol. 34 (2), 209-212
- https://doi.org/10.1136/thx.34.2.209
Abstract
59Fe-labeled human lactoferrin was preferentially ingested by mouse alveolar macrophages (MAM) when compared to 59Fe-labeled human transferrin. The cells bound and ingested 125I-labeled Fe-saturated and Fe-free lactoferrin. The latter was digested faster (t 1/2 [half-life] = 5.8 h) than the Fe-saturated compound (t 1/2 = 10.5 h). The constant elimination of the Fe-lactoferrin complex by alveolar macrophages could enhance the bacteriostatic effect of lactoferrin in the pulmonary secretions.This publication has 8 references indexed in Scilit:
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