Isocarboxazid Metabolism in Rat Liver Homogenate
- 1 July 1961
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 107 (3), 613-616
- https://doi.org/10.3181/00379727-107-26704
Abstract
Isocarboxazid was extensively metabolized under aerobic or anaerobic conditions in an in vitro system containing rat liver homogenate as the enzyme source. Benzylhydrazine was a major product of this metabolism as determined by paper chromatography and reverse isotope dilution in studies with C14-isocarboxazid. The possible occurrence of this pathway in vivo was discussed.Keywords
This publication has 2 references indexed in Scilit:
- PHARMACOLOGY OF IPRONIAZID AND OTHER AMINE OXIDASE INHIBITORSAnnals of the New York Academy of Sciences, 1959
- C-14-CHOLESTEROL .4. OXIDATION OF CARBON-4 AND CARBON-26 TO CARBON DIOXIDE BY SURVIVING TISSUES1952