A revolution in optical manipulation
Top Cited Papers
- 1 August 2003
- journal article
- review article
- Published by Springer Nature in Nature
- Vol. 424 (6950), 810-816
- https://doi.org/10.1038/nature01935
Abstract
Optical tweezers use the forces exerted by a strongly focused beam of light to trap and move objects ranging in size from tens of nanometres to tens of micrometres. Since their introduction in 1986, the optical tweezer has become an important tool for research in the fields of biology, physical chemistry and soft condensed matter physics. Recent advances promise to take optical tweezers out of the laboratory and into the mainstream of manufacturing and diagnostics; they may even become consumer products. The next generation of single-beam optical traps offers revolutionary new opportunities for fundamental and applied research.Keywords
This publication has 81 references indexed in Scilit:
- Binding strength and activation state of single fibrinogen-integrin pairs on living cellsProceedings of the National Academy of Sciences, 2002
- Trapping forces, force constants, and potential depths for dielectric spheres in the presence of spherical aberrationsApplied Optics, 2002
- History of optical trapping and manipulation of small-neutral particle, atoms, and moleculesIEEE Journal of Selected Topics in Quantum Electronics, 2000
- Three-dimensional high-resolution particle tracking for optical tweezers by forward scattered lightMicroscopy Research and Technique, 1999
- Characterization of trapping force on metallic Mie particlesApplied Optics, 1999
- Interference model for back-focal-plane displacement detection in optical tweezersOptics Letters, 1998
- Chapter 8 Signals and Noise in Micromechanical MeasurementsMethods in Cell Biology, 1997
- Measurement of small forces using an optical trapReview of Scientific Instruments, 1994
- Optical trapping of metallic Rayleigh particlesOptics Letters, 1994
- Observation of a single-beam gradient force optical trap for dielectric particlesOptics Letters, 1986