Failure of meningococcal vaccination to stop the transmission of meningococci in Nigerian schoolboys
- 1 April 1983
- journal article
- research article
- Published by Taylor & Francis in Pathogens and Global Health
- Vol. 77 (2), 175-178
- https://doi.org/10.1080/00034983.1983.11811694
Abstract
A combined group A and group C meningococcal polysaccharide vaccine was given to 438 Nigerian schoolboys shortly before an outbreak of group A meningococcal disease occurred in their school. Four months after vaccination the carriage rate of group A meningococci among vaccinated subjects (11%) was no different from that found among the controls (12%), although a good antibody response to both components of the vaccine was observed. One case of group A meningococcal disease was recorded amongst 438 vaccinated subjects while 5 cases occurred among 874 controls.This publication has 9 references indexed in Scilit:
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